Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327747 | 0.80 | APLNR (0.44) | APLNRKDM4EALDH1A1GAAMEN1 | |
| SCHEMBL24328889 | 0.80 | APLNR (0.44) | APLNRKDM4EALDH1A1GAAMEN1 | |
| SCHEMBL22295326 | 0.73 | MET (0.34) | ALDH1A1NPC1RAB9A | |
| SCHEMBL25581873 | 0.73 | APLNR (0.49) | APLNRGRM5JAK2 | |
| SCHEMBL15709789 | 0.72 | APLNR (0.45) | APLNRALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4023868 | 0.71 | APLNR (0.48) | APLNRALDH1A1GAAMEN1KMT2A | |
| SCHEMBL23578743 | 0.71 | APLNR (0.44) | APLNRGAAMEN1KMT2AFFAR2 | |
| SCHEMBL20392511 | 0.68 | APLNR (0.41) | APLNRGAAMEN1KMT2AFFAR2 | |
| SCHEMBL18558695 | 0.68 | APLNR (0.50) | APLNRFFAR2JAK2JAK1NPC1 | |
| SCHEMBL4023229 | 0.68 | APLNR (0.41) | APLNRALDH1A1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689866-A1 | QUINOLINE COMPOUND, AND BACTERICIDAL AGENT FOR AGRICULTURAL AND HORTICULTURAL USE | Nippon Soda Co., Ltd. (JP) | 2020-08-05 | — | — | EP | disclosed |