Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 9/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947864 | 0.80 | APLNR (0.42) | APLNRAGBL2 | |
| SCHEMBL31447986 | 0.77 | APLNR (0.42) | APLNRKMO | |
| SCHEMBL3923788 | 0.77 | APLNR (0.42) | APLNRKMO | |
| SCHEMBL3944958 | 0.77 | AGBL2 (0.38) | GRM5MAPK1ABL1AGBL2 | |
| SCHEMBL4025184 | 0.76 | APLNR (0.43) | APLNR | |
| SCHEMBL3946064 | 0.75 | CYP1A2 (0.45) | APLNRALDH1A1KMO | |
| Hydrochloric Acid SCHEMBL4974167 | 0.74 | APLNR (0.42) | APLNR | |
| SCHEMBL24327747 | 0.73 | APLNR (0.44) | APLNRGRM5ALDH1A1KMO | |
| SCHEMBL24328889 | 0.73 | APLNR (0.44) | APLNRGRM5ALDH1A1KMO | |
| SCHEMBL4023225 | 0.72 | MAPK1 (0.41) | APLNRGRM5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095712-A2 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-06 | — | — | WO | disclosed |