Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 5/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19392509 | 0.87 | HSD11B1 (0.47) | HSD11B1HTTSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL14364712 | 0.83 | HSD11B1 (0.43) | HSD11B1HTTSMN1; SMN2LMNAMMP2 | |
| SCHEMBL12236536 | 0.83 | HSD11B1 (0.43) | HSD11B1HTTSMN1; SMN2LMNAMMP2 | |
| SCHEMBL12463909 | 0.83 | HSD11B1 (0.43) | HSD11B1HTTSMN1; SMN2LMNAMMP2 | |
| SCHEMBL25971619 | 0.81 | KIF11 (0.48) | PTPN1HTTSMN1; SMN2CACNA1BTSHR | |
| SCHEMBL14365486 | 0.77 | HTT (0.61) | HSD11B1HTTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL822939 | 0.77 | HTT (0.61) | HSD11B1HTTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL19738900 | 0.77 | ALDH1A1 (0.49) | HSD11B1HTTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL18801597 | 0.77 | ALDH1A1 (0.49) | HSD11B1HTTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL22373765 | 0.77 | ALDH1A1 (0.49) | HSD11B1HTTSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481800-B1 | PROCESS FOR PREPARING AN ORGANIC SULFONE | BASF SE (DE) | 2020-08-05 | — | — | EP | disclosed |