SCHEMBL2229640

SCHEMBL2229640

C=C(CCCOCCOCCOC)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
EPHX2 P34913 2/20 0.35
TBXAS1 P24557 2/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TSHR P16473 3/20 0.32
KDM4E B2RXH2 2/20 0.31
CA2 P00918 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP3A4 P08684 2/20 0.31
ABCB11 O95342 1/20 0.31
ADRA2B P18089 1/20 0.31
OPRD1 P41143 1/20 0.31
SCN5A Q14524 1/20 0.31
TET2 Q6N021 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33440 1.00 ALDH1A1 (0.39) ALDH1A1EPHX2TBXAS1MEN1KMT2A
SCHEMBL4359174 0.93 THRB (0.40) ALDH1A1EPHX2TBXAS1SMN1; SMN2TSHR
SCHEMBL8928146 0.93 ALDH1A1 (0.50) ALDH1A1EPHX2TBXAS1MEN1KMT2A
SCHEMBL3800714 0.88 ALDH1A1 (0.38) ALDH1A1TBXAS1MEN1KMT2ASMN1; SMN2
SCHEMBL2230978 0.88 ALDH1A1 (0.38) ALDH1A1TBXAS1MEN1KMT2ASMN1; SMN2
SCHEMBL156151 0.88 ALDH1A1 (0.50) ALDH1A1TBXAS1MEN1KMT2ATSHR
SCHEMBL11126565 0.88 TSHR (0.39) ALDH1A1TBXAS1TSHRTET2
SCHEMBL13685002 0.87 ALDH1A1 (0.52) ALDH1A1EPHX2TBXAS1MEN1KMT2A
SCHEMBL13684994 0.87 ALDH1A1 (0.52) ALDH1A1EPHX2TBXAS1MEN1KMT2A
SCHEMBL5569902 0.85 ALDH1A1 (0.41) ALDH1A1EPHX2MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9096470-B2 Polymer of maleic acid, allyl ether and (meth)acrylic acid compounds, and preparation and use thereof SIKA TECHNOLOGY AG (CH) 2015-08-04 US disclosed
US-20140051801-A1 POLYMER OF MALEIC ACID, ALLYL ETHER AND (METH)ACRYLIC ACID COMPOUNDS, AND PREPARATION AND USE THEREOF SIKA TECHNOLOGY AG (CH) 2014-02-20 US disclosed
EP-2522680-B1 Polymer comprising maleic acid, allylether and (meth-)acrylic acid, its process of production and use SIKA TECHNOLOGY AG (CH) 2013-08-07 EP disclosed
WO-2012152766-A1 POLYMER OF MALEIC ACID, ALLYL ETHER AND (METH)ACRYLIC ACID COMPOUNDS, AND PREPARATION AND USE THEREOF SIKA TECHNOLOGY AG (CH) 2012-11-15 WO disclosed
EP-2522680-A1 Polymer comprising maleic acid, allylether and (meth-)acrylic acid, its process of production and use Sika Technology AG (CH) 2012-11-14 EP disclosed
WO-2011088929-A1 (METH)ACRYLATE POLYMERS FOR IMPROVING THE VISCOSITY INDEX EVONIK ROHMAX ADDITIVES GMBH (DE) 2011-07-28 WO disclosed