Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33440 | 0.93 | ALDH1A1 (0.39) | ALDH1A1EPHX2TBXAS1MEN1KMT2A | |
| SCHEMBL2229640 | 0.93 | ALDH1A1 (0.39) | ALDH1A1EPHX2TBXAS1MEN1KMT2A | |
| SCHEMBL13684994 | 0.91 | ALDH1A1 (0.52) | ALDH1A1EPHX2TBXAS1GAAMEN1 | |
| SCHEMBL13685002 | 0.91 | ALDH1A1 (0.52) | ALDH1A1EPHX2TBXAS1GAAMEN1 | |
| SCHEMBL16292006 | 0.89 | ALDH1A1 (0.63) | ALDH1A1EPHX2TBXAS1THRBKDM4E | |
| SCHEMBL16291990 | 0.89 | ALDH1A1 (0.63) | ALDH1A1EPHX2TBXAS1THRBKDM4E | |
| SCHEMBL16291638 | 0.89 | ALDH1A1 (0.63) | ALDH1A1EPHX2TBXAS1THRBKDM4E | |
| SCHEMBL523127 | 0.89 | ALDH1A1 (0.63) | ALDH1A1EPHX2TBXAS1THRBKDM4E | |
| SCHEMBL456879 | 0.87 | ALDH1A1 (0.59) | ALDH1A1EPHX2TBXAS1GAAMEN1 | |
| SCHEMBL4359174 | 0.86 | THRB (0.40) | ALDH1A1EPHX2TBXAS1THRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591204-B1 | PHARMACEUTICAL FORMULATIONS | BAUER KURT H (DE) | 1997-01-08 | — | — | EP | disclosed |