Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | IL17A | Q16552 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22297960 | 0.96 | RORC (0.50) | RORCSCN9ABRD4GAAIL17A | |
| SCHEMBL20870210 | 0.84 | RORC (0.51) | RORCSCN9AGAA | |
| SCHEMBL20529251 | 0.84 | RORC (0.51) | RORCSCN9AIL17ASLC6A9 | |
| SCHEMBL20870766 | 0.82 | BRD4 (0.42) | RORCBRD4GAASLC6A9 | |
| SCHEMBL20870474 | 0.82 | RORC (0.46) | RORCSCN9AIL17ASLC6A9 | |
| SCHEMBL5041677 | 0.81 | FABP4 (0.45) | SCN9ABRD4SLC6A9 | |
| SCHEMBL22262254 | 0.80 | RORC (0.47) | RORCSCN9AIL17ASLC6A9 | |
| SCHEMBL2828648 | 0.80 | SLC6A9 (0.53) | SCN9ABRD4SLC6A9 | |
| SCHEMBL20870201 | 0.78 | RORC (0.46) | RORCSCN9ABRD4 | |
| SCHEMBL5045383 | 0.78 | BRD4 (0.48) | BRD4SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689860-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS ROR INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-08-05 | — | — | EP | disclosed |