Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045383 | 0.95 | BRD4 (0.48) | FABP4FABP5BRD4S1PR3MAPK1 | |
| SCHEMBL1813202 | 0.86 | SLC6A9 (0.54) | BRD4S1PR3SLC6A9LMNA | |
| SCHEMBL5043148 | 0.83 | MAPK1 (0.49) | S1PR3MAPK1SLC6A9LMNARAB9A | |
| SCHEMBL5045483 | 0.81 | FABP4 (0.43) | FABP4FABP5MAPK1SLC6A9L3MBTL1 | |
| SCHEMBL2824930 | 0.81 | SLC6A9 (0.59) | BRD4S1PR3SLC6A9LMNA | |
| SCHEMBL3873090 | 0.81 | MAPK1 (0.56) | S1PR3MAPK1LMNARAB9ATSHR | |
| SCHEMBL22297948 | 0.81 | RORC (0.47) | BRD4SLC6A9SCN9A | |
| SCHEMBL22297960 | 0.80 | RORC (0.50) | BRD4SLC6A9SCN9A | |
| SCHEMBL2825503 | 0.79 | FABP4 (0.45) | FABP4FABP5MAPK1L3MBTL1APEX1 | |
| SCHEMBL20870766 | 0.79 | BRD4 (0.42) | BRD4MAPK1SLC6A9LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656361-B1 | PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |