SCHEMBL222988

SCHEMBL222988

Ic1ccc(SSc2ccc(I)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.44
MGLL Q99685 2/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
APP P05067 2/20 0.35
HDAC8 Q9BY41 2/20 0.35
TPMT P51580 1/20 0.35
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CYP3A4 P08684 3/20 0.32
IDO1 P14902 2/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
HIF1A Q16665 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SLC22A2 O15244 1/20 0.32
SLC22A1 O15245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13430074 0.91 MAPT (0.38) HSD17B10MGLLMAPTHPGDSMN1; SMN2
SCHEMBL5887631 0.79 CYP3A4 (0.47) MAPTHPGDMEN1KMT2AAPP
SCHEMBL10597056 0.76 HDAC8 (0.50) MGLLAPPHDAC8TPMTCA1
SCHEMBL67142 0.76
SCHEMBL24991865 0.73
SCHEMBL514288 0.73
SCHEMBL2018170 0.73
SCHEMBL9467719 0.73
Fluoride SCHEMBL27564048 0.71 HDAC8 (0.47) MGLLAPPHDAC8TPMTCA1
SCHEMBL21572118 0.68 APP (0.39) HPGDSMN1; SMN2MEN1KMT2AAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-12623120-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-12 US disclosed
US-12600837-B2 Rubber composition and crosslinked rubber molded product SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-14 US disclosed
EP-4527473-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2026-03-25 EP disclosed
US-12544628-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-02-10 US disclosed
US-20260027422-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-01-29 US disclosed
US-20250269241-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-08-28 US disclosed
US-12357881-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-07-15 US disclosed
US-20010024982-A1 Thin-layer-covered multilayer golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2001-09-27 US disclosed
US-6291592-B1 HARDNESS, STIFFNESS ACUSHNET COMPANY 2001-09-18 US disclosed
WO-2000038794-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038793-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING ELEMENTAL CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038795-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AROMATIC CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 US disclosed
US-5239052-A Heating aromatic disulfide in the presence of an aromatic halide HAY ALLAN S (CA) 1993-08-24 US disclosed
US-5177183-A Reaction of a halophenyl disulfide to form polyphenylene thioether HAY ALLAN S (CA) 1993-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027422-A1 GOLF BALL KIF5A, KIF5C, SURF4 HSD17B10 584/4885MGLL 2846/4885MAPT 3970/4885
US-12544628-B2 Golf ball KIF5A, KIF5C, SURF4 HSD17B10 707/4885MGLL 2718/4885MAPT 4138/4885
US-12623120-B2 Golf ball HSPH1, HSP90AB1, DYNC1H1 HSD17B10 1594/4885MGLL 3736/4885MAPT 3243/4885
US-12600837-B2 Rubber composition and crosslinked rubber molded product RER1, RIF1, SHC1 HSD17B10 2663/4885MGLL 2929/4885MAPT 3031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.