SCHEMBL223004

SCHEMBL223004

C=CNC(=O)CCC(N)=O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
FGFR4 P22455 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.32
KDM4E B2RXH2 1/20 0.31
KDM5C P41229 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10594684 0.88 MAPT (0.45) ALDH1A1TSHRFGFR4SMN1; SMN2MAPT
SCHEMBL11055881 0.88 TSHR (0.45) ALDH1A1TSHRFGFR4SMN1; SMN2MAPT
SCHEMBL31364147 0.81 KDM4E (0.52) ALDH1A1TSHRSMN1; SMN2MAPTKDM4E
Octadecanoic Acid Amide SCHEMBL27917530 0.78 FAAH (0.55) TSHRKDM4E
SCHEMBL24309157 0.78
SCHEMBL499105 0.78 KDM4E (0.32) KDM4EKDM5CPHF8KDM2A
SCHEMBL223005 0.78 PHF8 (0.50) ALDH1A1TSHRMAPTKDM4EKDM5C
SCHEMBL4891885 0.76
SCHEMBL8440530 0.75
SCHEMBL29158015 0.75 TSHR (0.50) ALDH1A1TSHRSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120195937-A1 POLYANIONIC POLYMER ADJUVANTS FOR HAEMOPHILUS INFLUENZAE B SACCHARIDE VACCINES GLAXOSMITHKLINE BIOLOGICALS, S.A. (BE) 2012-08-02 US claimed
US-20060121059-A1 Vaccine composition GLAXOSMTHKLINE BIOLOGICALS, S.A. (BE) 2006-06-08 US claimed
EP-1638597-A2 POLYANIONIC POLYMER ADJUVANTS FOR HAEMOPHILUS INFLUENZA B SACCHARIDE VACCINES GlaxoSmithKline Biologicals S.A. (BE) 2006-03-29 EP claimed
EP-1034194-B1 POLY(VINYLAMINE)-BASED SUPERABSORBENT GELS AND METHOD OF MANUFACTURING THE SAME BASF AG (DE) 2006-03-01 EP claimed
WO-2004110480-A2 POLYANIONIC POLYMER ADJUVANTS FOR HAEMOPHILUS INFLUENZA B SACCHARIDE VACCINES GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) 2004-12-23 WO claimed
US-6610310-B2 Immunology response; side effect reduction AMERICAN CYANAMID COMPANY 2003-08-26 US claimed
US-20030021793-A1 POLYANIONIC POLYMERS AS ADJUVANTS FOR MUCOSAL IMMUNIZATION ZOETIS SERVICES LLC 2003-01-30 US claimed
EP-1034194-A1 POLY(VINYLAMINE)-BASED SUPERABSORBENT GELS AND METHOD OF MANUFACTURING THE SAME AMCOL INTERNATIONAL CORPORATION (US) 2000-09-13 EP claimed
US-5981689-A FORMING A MONOMER MIXTURE COMPRISING AN N-VINYLAMIDE, 0% TO 90% BY WEIGHT OF ONE OR MORE MONOETHYLENICALLY UNSATURATED MONOMERS, AND 0% TO ABOUT 10% OF A POLYVINYL MONOMER, POLYMERIZING MONOMERS, ADDING SCAVENGING AGENT AMCOL INTERNATIONAL CORPORATION (US) 1999-11-09 US claimed
EP-0934077-A2 POLYANIONIC POLYMERS AS ADJUVANTS FOR MUCOSAL IMMUNIZATION DIMMINACO AG/SA/LTD. (CH) 1999-08-11 EP claimed
WO-1999025745-A1 POLY(VINYLAMINE)-BASED SUPERABSORBENT GELS AND METHOD OF MANUFACTURING THE SAME AMCOL INTERNATIONAL CORPORATION (US) 1999-05-27 WO claimed
WO-1998017310-A2 POLYANIONIC POLYMERS AS ADJUVANTS FOR MUCOSAL IMMUNIZATION DIMMINACO AG/S.A./LTD. (CH) 1998-04-30 WO claimed
US-5516619-A Conductive composite particles and processes for the preparation thereof XEROX CORPORATION (US) 1996-05-14 US claimed
US-5484681-A Conductive composite particles and processes for the preparation thereof XEROX CORPORATION (US) 1996-01-16 US claimed
EP-0188110-B1 Hydrogel-forming polymers TR DEV LTD (GB) 1995-09-06 EP claimed
US-5288585-A Processes for the preparation of polymers XEROX CORPORATION (US) 1994-02-22 US claimed
US-4110244-A Photochromic plastic material AMERICAN OPTICAL CORPORATION (US) 1978-08-29 US claimed
US-4049846-A Photochromic plastic materials AMERICAN OPTICAL CORPORATION (US) 1977-09-20 US claimed
US-20260091055-A1 Methods of Managing Traumatic Brain Injury UNIV EMORY (US) 2026-04-02 US disclosed
US-3939130-A Polymers of monomers containing active methylene groups and other ethylenically unsaturated monomers INDICON INC. (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091055-A1 Methods of Managing Traumatic Brain Injury SGMS2, SGMS1, S1PR2 ALDH1A1 4310/4885TSHR 3353/4885FGFR4 2295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.