Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568167 | 0.91 | CYP19A1 (0.51) | ALDH1A1CYP19A1GAACA1CA2 | |
| SCHEMBL28614521 | 0.90 | LTA4H (0.46) | ESR2ALDH1A1CYP19A1GAACA1 | |
| SCHEMBL29509424 | 0.90 | MEN1 (0.45) | ESR1ESR2ALDH1A1CYP3A4CYP19A1 | |
| SCHEMBL4599958 | 0.88 | CYP19A1 (0.48) | ALDH1A1CYP19A1GAACA1CA2 | |
| SCHEMBL28610925 | 0.85 | MEN1 (0.40) | ESR1ESR2CYP3A4CYP19A1GAA | |
| SCHEMBL28608386 | 0.84 | CYP19A1 (0.38) | ESR1ESR2ALDH1A1CYP3A4CYP19A1 | |
| SCHEMBL17942478 | 0.81 | MAPT (0.50) | ALDH1A1CYP3A4CYP19A1GAACA1 | |
| SCHEMBL8784494 | 0.80 | CA1 (0.55) | ALDH1A1CYP3A4CYP19A1GAACA1 | |
| SCHEMBL10740520 | 0.79 | MEN1 (0.46) | ESR1ESR2ALDH1A1CYP3A4GAA | |
| SCHEMBL20675 | 0.78 | CYP19A1 (0.45) | ALDH1A1CYP3A4CYP19A1GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12338193-B2 | Methods for enantioselective preparation of chiral tetraarylmethanes | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-06-24 | — | — | US | disclosed |
| CN-113302172-B | Enantioselective preparation of chiral tetraarylmethanes | 香港科技大学 | 2023-12-01 | — | — | CN | disclosed |
| US-20220112138-A1 | METHODS FOR ENANTIOSELECTIVE PREPARATION OF CHIRAL TETRAARYLMETHANES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-04-14 | — | — | US | disclosed |
| CN-113302172-A | Enantioselective preparation of chiral tetraarylmethanes | 香港科技大学 | 2021-08-24 | — | — | CN | disclosed |
| WO-2020156022-A1 | METHODS FOR ENANTIOSELECTIVE PREPARATION OF CHIRAL TETRAARYLMETHANES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12338193-B2 | Methods for enantioselective preparation of chiral tetraarylmethanes | HMBS, CYP4F3, HMGCR | ESR1 3450/4885ESR2 3447/4885ALDH1A1 2013/4885 |
| US-20220112138-A1 | METHODS FOR ENANTIOSELECTIVE PREPARATION OF CHIRAL TETRAARYLMETHANES | HMBS, CYP4F3, HMGCR | ESR1 3450/4885ESR2 3447/4885ALDH1A1 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.