Sugi Predict

Sugi Predict / Compounds / SCHEMBL20675

SCHEMBL20675

SCHEMBL20675

COc1cccc(C(O)(c2ccccc2)c2ccccc2)c1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 2/20 0.45
▸ NFE2L2 Q16236 2/20 0.42
▸ CRHBP P24387 1/20 0.41
▸ CRHR2 Q13324 1/20 0.41
▸ CA1 P00915 3/20 0.40
▸ CA2 P00918 3/20 0.40
▸ CA12 O43570 2/20 0.40
▸ CA7 P43166 2/20 0.40
▸ CA9 Q16790 2/20 0.40
▸ CA14 Q9ULX7 2/20 0.40
▸ GAA P10253 2/20 0.40
▸ CA4 P22748 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ TP53 P04637 2/20 0.38
▸ TSHR P16473 1/20 0.38
▸ NR3C2 P08235 1/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ TRPM8 Q7Z2W7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6568167 0.85 CYP19A1 (0.51) CYP19A1CRHBPCRHR2CA1CA2
SCHEMBL18550496 0.83 NFE2L2 (0.41) NFE2L2CA1CA2CA12CA7
SCHEMBL17942478 0.83 MAPT (0.50) CYP19A1CRHBPCRHR2CA1CA2
SCHEMBL16675115 0.82 NFE2L2 (0.45) NFE2L2CA1CA2CA12CA7
SCHEMBL4599958 0.82 CYP19A1 (0.48) CYP19A1CRHBPCRHR2CA1CA2
SCHEMBL9013823 0.81 NFE2L2 (0.44) NFE2L2CA1CA2CA12CA7
SCHEMBL136230 0.81 NFE2L2 (0.44) NFE2L2CA1CA2CA12CA7
SCHEMBL7713130 0.81 NFE2L2 (0.44) NFE2L2CA1CA2CA12CA7
SCHEMBL27926604 0.81 NFE2L2 (0.44) NFE2L2CA1CA2CA12CA7
SCHEMBL31430103 0.81 NFE2L2 (0.44) NFE2L2CA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243540-A1 PROBE RELATED REAGENTS AND METHODS BRENTANO BIOTECHNOLOGY ASSOCIATES (US) 2025-07-31 — — US disclosed
EP-2609107-B1 BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) 2024-12-11 — — EP disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 — — US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 — — US disclosed
EP-4034131-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES Brentano Biotechnology Associates (US) 2022-08-03 — — EP disclosed
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 — — EP disclosed
US-20220073546-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES BRENTANO BIOTECHNOLOGY ASSOCIATES (US) 2022-03-10 — — US disclosed
EP-3592393-B1 RELEASABLE CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2021-12-01 — — EP disclosed
US-20210300954-A1 IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2021-09-30 — — US disclosed
CN-103889999-B Ion labeling for oligoribonucleotide synthesis 皇家学习促进学会/麦吉尔大学 2021-06-01 — — CN disclosed
EP-0164054-A1 Method for detection of polymorphic restriction sites and nucleic acid sequences CETUS CORPORATION (US) 1985-12-11 — — EP disclosed
US-4500707-A Nucleosides useful in the preparation of polynucleotides UNIVERSITY PATENTS, INC. (US) 1985-02-19 — — US disclosed
EP-0131043-A1 PROCESS FOR PRODUCING POLYNUCLEOTIDES Board of Trustees of Southern Illinois University (US) 1985-01-16 — — EP disclosed
EP-0130564-A1 Modified (80-113) beta interferons G.D. Searle & Co. (US) 1985-01-09 — — EP disclosed
EP-0130565-A1 Modified (115-145) beta interferons G.D. Searle & Co. (US) 1985-01-09 — — EP disclosed
EP-0130566-A1 Modified (1-28) beta interferons G.D. Searle & Co. (US) 1985-01-09 — — EP disclosed
EP-0115613-A2 DNA sequences, their preparation, plasmids containing these sequences and their use in the synthesis of eukaryotic gene products in prokaryotes BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) 1984-08-15 — — EP disclosed
WO-1984002526-A1 PROCESS FOR PRODUCING POLYNUCLEOTIDES UNIV SOUTHERN ILLINOIS (US) 1984-07-05 — — WO disclosed
US-4458066-A BOUND TO INORGANIC SUPPORT UNIVERSITY PATENTS, INC. (US) 1984-07-03 — — US disclosed
EP-0068375-A2 Recombinant DNA techniques for the production of relaxin G.D. Searle & Co. (US) 1983-01-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210300954-A1 IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES RNGTT, OSTC, DTYMK CYP19A1 4803/4885NFE2L2 4571/4885CRHBP 2021/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 CYP19A1 169/4885NFE2L2 3178/4885CRHBP 1890/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 CYP19A1 169/4885NFE2L2 3178/4885CRHBP 1890/4885
US-20250243540-A1 PROBE RELATED REAGENTS AND METHODS DNTT, NCL, NT5C3B CYP19A1 4269/4885NFE2L2 3707/4885CRHBP 1304/4885
US-20220073546-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES NCL, PCNA, DNTT CYP19A1 4474/4885NFE2L2 3852/4885CRHBP 1512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.