SCHEMBL6568167

SCHEMBL6568167

COc1ccccc1C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.51
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA12 O43570 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA4 P22748 1/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
ALDH1A1 P00352 2/20 0.45
NR3C2 P08235 1/20 0.44
GAA P10253 3/20 0.44
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HTT P42858 2/20 0.42
CASR P41180 1/20 0.42
ENPP2 Q13822 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4599958 0.96 CYP19A1 (0.48) CYP19A1CA1CA2CA7CA9
SCHEMBL22301044 0.91 ESR1 (0.47) CYP19A1CA1CA2CA7CA9
SCHEMBL8784494 0.87 CA1 (0.55) CYP19A1CA1CA2CA7CA9
SCHEMBL20675 0.85 CYP19A1 (0.45) CYP19A1CA1CA2CA7CA9
SCHEMBL17942478 0.85 MAPT (0.50) CYP19A1CA1CA2CA7CA9
SCHEMBL18545738 0.82 CASR (0.51) CA1CA2CA7CA9CA12
SCHEMBL2795840 0.82 KMT2A (0.56) CA1CA2CA7CA9CA12
SCHEMBL28614521 0.81 LTA4H (0.46) CYP19A1CA1CA2ALDH1A1GAA
SCHEMBL29509424 0.81 MEN1 (0.45) CYP19A1CA1CA2CA7CA9
SCHEMBL238442 0.81 ALDH1A1 (0.43) CYP19A1CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1447408-A1 Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and therapeutics produced therewith Rohm and Haas Company (US) 2004-08-18 EP disclosed
US-20040158037-A1 Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and biologically active substances and therapeutics produced therewith BOHLING JAMES CHARLES (US) 2004-08-12 US disclosed
EP-0703498-B1 Photosensitive resin composition and method for forming a photoresist pattern MITSUBISHI CHEM CORP (JP) 1997-12-29 EP disclosed
US-5698362-A CONTAINING A TRIARYLMETHANE DERIVATIVE; HIGH RESOLUTION, EXCELLENT IN DEPTH OF FOCUS AND PATTERN PROFILE, STORAGE STABLE MITSUBISHI CHEMICAL CORPORATION (JP) 1997-12-16 US disclosed
EP-0703498-A1 Photosensitive resin composition and method for forming a photoresist pattern MITSUBISHI CHEMICAL CORPORATION (JP) 1996-03-27 EP disclosed
CN-87105787-A The thermostability enzyme of purifying and with its increase, the method for detection and/or cloning nucleic acid sequences 1988-05-11 CN disclosed