Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | REN | P00797 | 3/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.47 |
| ▸ | CCKBR | P32239 | 3/20 | 0.47 |
| ▸ | CCKAR | P32238 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23447158 | 0.88 | REN (0.60) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL22301095 | 0.84 | CTSS (0.52) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL7408909 | 0.84 | CTSS (0.57) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL20216484 | 0.84 | CTSS (0.63) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL20030538 | 0.84 | CTSS (0.63) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL18154504 | 0.83 | ACE (0.69) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL30487469 | 0.83 | ACE (0.69) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL10688353 | 0.83 | ACE (0.69) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL23447618 | 0.83 | REN (0.52) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL24084059 | 0.83 | REN (0.64) | CTSSCTSKCTSBCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |
| WO-2020155497-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2020-08-06 | — | — | WO | disclosed |