SCHEMBL28627397

SCHEMBL28627397

C=C(C)C(=O)OC(C)OCCOc1ccc(C2(c3ccc(OCCOC(C)OC(=O)C(=C)C)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PDK2 Q15119 11/20 0.34
MAPT P10636 3/20 0.34
LMNA P02545 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
OPRK1 P41145 1/20 0.33
CHRM5 P08912 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2230357 0.88 PDK2 (0.39) POLBAPEX1HTTTDP1PDK2
SCHEMBL534806 0.85 PDK2 (0.39) POLBAPEX1HTTTDP1PDK2
SCHEMBL534651 0.84 POLB (0.36) POLBAPEX1HTTTDP1PDK2
SCHEMBL157502 0.84 POLB (0.48) POLBAPEX1HTTTDP1PDK2
SCHEMBL30800968 0.84 POLB (0.48) POLBAPEX1HTTTDP1PDK2
SCHEMBL1264240 0.82 MTNR1A (0.44) POLBAPEX1HTTTDP1MAPT
SCHEMBL14889149 0.81 POLB (0.45) POLBAPEX1HTTTDP1PDK2
SCHEMBL534807 0.81 POLB (0.53) POLBAPEX1HTTTDP1PDK2
SCHEMBL3760944 0.80 PDK2 (0.41) POLBPDK2MAPTLMNAMEN1
SCHEMBL20110392 0.80 POLB (0.41) POLBAPEX1HTTTDP1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106414525-B Photocurable resin composition 电化株式会社 2021-09-21 CN disclosed