Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22305337 | 0.85 | PRMT5 (0.31) | OGA | |
| SCHEMBL22306193 | 0.80 | RAB9A (0.46) | — | |
| SCHEMBL22306196 | 0.76 | CCR2 (0.34) | OGA | |
| SCHEMBL22306616 | 0.74 | L3MBTL1 (0.32) | — | |
| SCHEMBL22306210 | 0.73 | — | — | |
| SCHEMBL22306478 | 0.68 | POLB (0.34) | — | |
| SCHEMBL22305371 | 0.67 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL22306597 | 0.67 | — | — | |
| SCHEMBL22306202 | 0.66 | NPC1 (0.31) | — | |
| SCHEMBL22306207 | 0.63 | RAB9A (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |