SCHEMBL2230702

SCHEMBL2230702

NN(C(=S)Nc1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
TAS2R38 P59533 3/20 0.52
HSD17B10 Q99714 2/20 0.52
TP53 P04637 1/20 0.52
TYR P14679 1/20 0.52
TSHR P16473 1/20 0.52
CYP3A4 P08684 1/20 0.50
CYP1A2 P05177 1/20 0.47
GAA P10253 5/20 0.47
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
NOX1 Q9Y5S8 1/20 0.47
MAPT P10636 4/20 0.46
PHGDH O43175 1/20 0.45
KDM4E B2RXH2 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HPGD P15428 1/20 0.43
THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9297667 0.83 ALDH1A1 (0.54) ALDH1A1TAS2R38HSD17B10TP53TYR
SCHEMBL11702071 0.79 ALDH1A1 (0.50) ALDH1A1TAS2R38HSD17B10TP53TYR
SCHEMBL7841167 0.78 L3MBTL1 (0.62) ALDH1A1CYP1A2GAAKMT2AMEN1
SCHEMBL10670402 0.78 MEN1 (0.67) ALDH1A1TAS2R38HSD17B10TP53TYR
SCHEMBL11366683 0.77 ALDH1A1 (0.48) ALDH1A1TAS2R38HSD17B10TP53TYR
SCHEMBL15375764 0.77 ALDH1A1 (0.53) ALDH1A1TAS2R38HSD17B10TP53TYR
SCHEMBL8701487 0.77 ALDH1A1 (0.63) ALDH1A1TAS2R38HSD17B10TP53TYR
SCHEMBL10394940 0.76 LMNA (0.66) ALDH1A1TAS2R38HSD17B10CYP3A4CYP1A2
SCHEMBL11726723 0.76 MEN1 (0.56) ALDH1A1HSD17B10TP53TSHRGAA
SCHEMBL9470195 0.76 ALDH1A1 (0.50) ALDH1A1TAS2R38HSD17B10TP53TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2343339-B1 ADHESIVE COMPOSITION AND ADHESION METHOD DENKA COMPANY LTD (JP) 2017-01-18 EP disclosed
CN-103819376-A Dichloro salicylaldehyde thiourea derivative and application thereof UNIV GUILIN TECH GUT 2014-05-28 CN disclosed
CN-103787940-A Dimethyl aminobenzaldehyde thiourea derivative and application thereof UNIV GUILIN TECH GUT 2014-05-14 CN disclosed
EP-2194105-B1 ADHESIVE COMPOSITIONS AND JOINTING METHOD DENKI KAGAKU KOGYO KK (JP) 2013-05-08 EP disclosed
US-8323448-B2 Adhesive composition and bonding method DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2012-12-04 US disclosed
US-8273827-B2 Adhesive composition and adhesion method DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2012-09-25 US disclosed
US-20110190414-A1 ADHESIVE COMPOSITION AND ADHESION METHOD DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2011-08-04 US disclosed
EP-2343339-A1 ADHESIVE COMPOSITION AND ADHESION METHOD Denki Kagaku Kogyo Kabushiki Kaisha (JP) 2011-07-13 EP disclosed
US-20100236716-A1 ADHESIVE COMPOSITION AND BONDING METHOD DENKI KAGAKU KOGYO KABUSHIKI KAISHA, (JP) 2010-09-23 US disclosed
EP-2194105-A1 ADHESIVE COMPOSITIONS AND JOINTING METHOD Denki Kagaku Kogyo Kabushiki Kaisha (JP) 2010-06-09 EP disclosed
US-5831097-A TRIAZOLIUM SALT REACTIVE CATALYST, ALDEHYDE CONDENSATION BASF AKTIENGESELLSCHAFT (DE) 1998-11-03 US disclosed
US-5585496-A REACTING TRIAZOLIUM SALT WITH ALKANOLATE OR THIOLATE TO FORM ADDITION COMPOUND USED AS CATALYST FOR FORMALDEHYDE CONDENSATION BASF AKTIENGESELLSCHAFT (DE) 1996-12-17 US disclosed
US-5508422-A USEFUL AS CATALYSTS IN FORMING CONDENSATION PRODUCTS OF FORMALDEHYDE BASF AKTIENGESELLSCHAFT (DE) 1996-04-16 US disclosed
US-5386062-A Triazole or tetrazole compounds BASF AKTIENGESELLSCHAFT (DE) 1995-01-31 US disclosed
US-4424363-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1984-01-03 US disclosed
US-4354031-A HERBICIDES BASF ATIENGESELLSCHAFT (DE) 1982-10-12 US disclosed
US-4316039-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US disclosed
US-4260775-A Substituted 3-aminopyrazoles BASF AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
EP-0002180-A1 Substituted 3-aminopyrazoles, herbicides containing them and method for controlling undesirable growth of plants BASF Aktiengesellschaft (DE) 1979-06-13 EP disclosed