Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810689 | 0.83 | L3MBTL1 (0.67) | L3MBTL1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11702071 | 0.81 | ALDH1A1 (0.50) | L3MBTL1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7843193 | 0.80 | L3MBTL1 (0.40) | L3MBTL1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2230702 | 0.78 | ALDH1A1 (0.52) | L3MBTL1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL9327091 | 0.78 | ALDH1A1 (0.52) | L3MBTL1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6694830 | 0.77 | LMNA (1.00) | L3MBTL1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11445188 | 0.77 | L3MBTL1 (0.64) | L3MBTL1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6768370 | 0.76 | ALDH1A1 (0.54) | L3MBTL1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11726572 | 0.75 | NPSR1 (0.46) | L3MBTL1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10894662 | 0.75 | ALDH1A1 (0.58) | L3MBTL1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077954-A1 | SUBSTITUTED 6-ARYL-3-THIOXO-5-(THI)OXO-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINES | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059983-A1 | SUBSTITUTED 6-ARYL-3-THIOXO-5-(THI)OXO-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |