SCHEMBL22307183

SCHEMBL22307183

COC(C)OC(=N)c1cccc(Br)c1C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22307186 0.85 F2R (0.33)
SCHEMBL21636760 0.80 NPC1 (0.36) ALDH1A1CYP2C19
SCHEMBL22307927 0.80
SCHEMBL21842993 0.77 F2R (0.40) ALDH1A1CYP3A4
SCHEMBL22308161 0.76 ALDH1A1 (0.33) ALDH1A1
SCHEMBL5841557 0.69 NPC1 (0.50) ALDH1A1CYP2C19
SCHEMBL4509521 0.69 C1S (0.39) ALDH1A1
SCHEMBL2134095 0.67 SMN1; SMN2 (0.37) ALDH1A1
SCHEMBL10665661 0.66 TSHR (0.47) ALDH1A1
SCHEMBL257409 0.66 LMNA (0.50) ALDH1A1ALOX15CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022022600-A1 IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF BETTA PHARMACEUTICALS CO., LTD (CN) 2022-02-03 WO disclosed
WO-2020156323-A1 IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF BETTA PHARMACEUTICALS CO., LTD (CN) 2020-08-06 WO disclosed