Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17543775 | 0.79 | SRD5A1 (0.36) | MEN1KMT2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL22491528 | 0.74 | CRBN (0.49) | MEN1KMT2ACA9CRBNALDH1A1 | |
| SCHEMBL29734620 | 0.74 | CRBN (0.49) | MEN1KMT2ACA9CRBNALDH1A1 | |
| SCHEMBL9596541 | 0.73 | CYP11B1 (0.42) | PDE3BPDE3AMEN1TSHRCYP2C19 | |
| SCHEMBL14509052 | 0.72 | ACHE (0.39) | KMT2ADAOSELLSELPSELE | |
| SCHEMBL98299 | 0.70 | NPC1 (0.50) | CYP19A1CYP11B1CYP11B2NPC1MAPK13 | |
| SCHEMBL29863302 | 0.70 | NPC1 (0.50) | CYP19A1CYP11B1CYP11B2NPC1MAPK13 | |
| SCHEMBL12902087 | 0.70 | MEN1 (0.42) | PDE3BPDE3AMEN1TSHRCYP2C19 | |
| SCHEMBL22312385 | 0.69 | UHRF1 (0.40) | MEN1KMT2ASELLSELPSELE | |
| SCHEMBL22312376 | 0.69 | PDE3B (0.53) | PDE3BPDE3AMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156162-A1 | MEK INHIBITOR AND PHARMACEUTICAL USE THEREOF | 贝达药业股份有限公司 | 2020-08-06 | — | — | WO | disclosed |