Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494395 | 0.78 | CYP11B2 (0.38) | CYP11B1CYP11B2CYP19A1NPC1MAPK13 | |
| SCHEMBL29050349 | 0.74 | CYP11B1 (0.44) | CYP11B1CYP11B2CYP19A1NPC1MAPK13 | |
| SCHEMBL22753803 | 0.73 | CYP2C19 (0.44) | CYP11B1CYP11B2NPC1MAPK13MAPK12 | |
| SCHEMBL22311512 | 0.73 | PDE3B (0.37) | CYP11B1CYP11B2CYP19A1NPC1MAPK13 | |
| SCHEMBL17543775 | 0.73 | SRD5A1 (0.36) | CYP11B1CYP11B2CYP19A1NPC1MAPK13 | |
| SCHEMBL98299 | 0.72 | NPC1 (0.50) | CYP11B1CYP11B2CYP19A1NPC1MAPK13 | |
| SCHEMBL29863302 | 0.72 | NPC1 (0.50) | CYP11B1CYP11B2CYP19A1NPC1MAPK13 | |
| SCHEMBL30731334 | 0.68 | NPC1 (0.37) | CYP11B1CYP11B2CYP19A1NPC1MAPK13 | |
| SCHEMBL6407953 | 0.66 | MAPT (0.53) | CYP11B1CYP11B2CYP19A1NPC1MAPK13 | |
| SCHEMBL2233749 | 0.64 | NPC1 (0.55) | CYP11B1CYP11B2CYP19A1NPC1MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260177-A | Cyan dye-forming coupler, pivaloylacetoanilide yellow coupler, pyrazoloazole magenta coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1993-11-09 | — | — | US | disclosed |