SCHEMBL223127

SCHEMBL223127

CCC[C@H]1CC[C@H](C(=O)O)CC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.56
PLG P00747 1/20 0.56
PLAT P00750 1/20 0.56
ANPEP P15144 1/20 0.44
ENPEP Q07075 1/20 0.44
CYP2C9 P11712 3/20 0.42
POLB P06746 1/20 0.41
HPGD P15428 1/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 2/20 0.40
HTT P42858 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPK1 P28482 1/20 0.40
PKM P14618 1/20 0.40
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
TSHR P16473 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3512672 1.00 LMNA (0.56) LMNAPLGPLATANPEPENPEP
SCHEMBL223128 1.00 LMNA (0.56) LMNAPLGPLATANPEPENPEP
SCHEMBL3191994 0.98 LMNA (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL3192001 0.98 LMNA (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL10480023 0.98 LMNA (0.54) LMNAPLGPLATANPEPENPEP
Hydrochloric Acid SCHEMBL7876220 0.98 LMNA (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL10480026 0.98 LMNA (0.54) LMNAPLGPLATANPEPENPEP
Hydrochloric Acid SCHEMBL9338669 0.98 LMNA (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL1310398 0.94 LMNA (0.50) LMNAPLGPLATANPEPENPEP
SCHEMBL10797749 0.94 LMNA (0.50) LMNAPLGPLATANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0363451-B2 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1999-12-15 EP claimed
EP-0285617-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1991-12-27 EP claimed
EP-0033947-B2 LIQUID CRYSTAL DISPLAY ELEMENT KABUSHIKI KAISHA TOSHIBA (JP) 1987-01-14 EP claimed
EP-0033947-B1 LIQUID CRYSTAL DISPLAY ELEMENT KABUSHIKI KAISHA TOSHIBA (JP) 1983-09-21 EP claimed
JP-9040606-A None JP disclosed
JP-3261754-A None JP disclosed
CN-113710654-B Polymerizable liquid crystal having carbazole nucleus 罗利克技术有限公司 2024-08-30 CN disclosed
US-12012382-B2 Polymerizable liquid crystal having a carbazole core Rolic Technologies AG (CH) 2024-06-18 US disclosed
CN-113980686-B Preparation method of lateral o-difluorobenzene liquid crystal compound containing cyclohexyl 宁夏中星显示材料有限公司 2023-10-10 CN disclosed
CN-113881442-B Liquid crystal compound containing polyfluornonaphthalene and preparation method thereof 宁夏中星显示材料有限公司 2023-02-03 CN disclosed
US-20220259148-A1 NEW POLYMERIZABLE LIQUID CRYSTAL HAVING A CARBAZOLE CORE Rolic Technologies AG (CH) 2022-08-18 US disclosed
EP-3990430-A1 NEW POLYMERIZABLE LIQUID CRYSTAL HAVING A CARBAZOLE CORE Rolic Technologies AG (CH) 2022-05-04 EP disclosed
US-4462923-A Disubstituted pyrimidines HOFFMANN-LA ROCHE INC. (US) 1984-07-31 US disclosed
EP-0107759-A2 Cyclohexane derivatives and their use as components for liquid crystals MERCK PATENT GmbH (DE) 1984-05-09 EP disclosed
EP-0103681-A1 Tetra- and pentacyclic monoesters F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-03-28 EP disclosed
EP-0030761-B1 ANISOTROPIC CYCLOHEXYL ETHERS MERCK PATENT GmbH (DE) 1984-03-21 EP disclosed
US-4361494-A Anisotropic cyclohexyl cyclohexylmethyl ethers BBC BROWN, BOVERI, & COMPANY, LIMITED (CH) 1982-11-30 US disclosed
US-4290905-A FOR LIQUID CRYSTAL DISPLAYS KABUSHIKI KAISHA SUWA SEIKOSHA (JP) 1981-09-22 US disclosed
EP-0030761-A1 Anisotropic cyclohexyl ethers MERCK PATENT GmbH (DE) 1981-06-24 EP disclosed
US-4261651-A CYCLOHEXANE CONTAINING DERIVATIVES OF AROMATIC NITRILES THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1981-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12012382-B2 Polymerizable liquid crystal having a carbazole core FZD7, CCL11, SGK2 LMNA 2536/4885PLG 3420/4885PLAT 4394/4885
US-20220259148-A1 NEW POLYMERIZABLE LIQUID CRYSTAL HAVING A CARBAZOLE CORE FZD7, CXXC5, SGK2 LMNA 2234/4885PLG 3279/4885PLAT 4402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.