SCHEMBL3192001

SCHEMBL3192001

CCCC1CCC(CCC2CCC(C(=O)O)CC2)CC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
PLG P00747 1/20 0.54
PLAT P00750 1/20 0.54
ANPEP P15144 1/20 0.47
ENPEP Q07075 1/20 0.47
CYP2C9 P11712 3/20 0.41
POLB P06746 1/20 0.40
HPGD P15428 1/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 2/20 0.39
ALDH1A1 P00352 2/20 0.39
PKM P14618 1/20 0.39
HTT P42858 2/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10480026 1.00 LMNA (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL3191994 1.00 LMNA (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL10480023 1.00 LMNA (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL223127 0.98 LMNA (0.56) LMNAPLGPLATANPEPENPEP
SCHEMBL223128 0.98 LMNA (0.56) LMNAPLGPLATANPEPENPEP
SCHEMBL3512672 0.98 LMNA (0.56) LMNAPLGPLATANPEPENPEP
Hydrochloric Acid SCHEMBL7876220 0.96 LMNA (0.54) LMNAPLGPLATANPEPENPEP
Hydrochloric Acid SCHEMBL9338669 0.96 LMNA (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL10797749 0.92 LMNA (0.50) LMNAPLGPLATANPEPENPEP
SCHEMBL1310398 0.92 LMNA (0.50) LMNAPLGPLATANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1852411-B1 TRIFLUORONAPHTHALENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE COMPOUND DAINIPPON INK & CHEMICALS (JP) 2010-11-10 EP disclosed
US-7662442-B2 Trifluoronaphthalene derivative and liquid crystal composition containing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2010-02-16 US disclosed
US-20090121186-A1 TRIFLUORONAPHTHALENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME DAINIPPON INK AND CHEMICALS, INC. (JP) 2009-05-14 US disclosed
US-20090121186-A1 TRIFLUORONAPHTHALENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME DAINIPPON INK AND CHEMICALS, INC. (JP) 2009-05-14 US disclosed
EP-1852411-A1 TRIFLUORONAPHTHALENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE COMPOUND DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-11-07 EP disclosed
US-4871470-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090121186-A1 TRIFLUORONAPHTHALENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME TCF4, DVL1, TCF12 LMNA 1477/4885PLG 3648/4885PLAT 2810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.