Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229954 | 0.80 | KDM4E (0.41) | KDM4EMAPTCYP3A4NR4A2SYK | |
| SCHEMBL2229343 | 0.80 | ADRB2 (0.44) | KDM4EMAPTCYP3A4NR4A2SYK | |
| SCHEMBL2230186 | 0.79 | MAOA (0.41) | KDM4EMAPTRAB9ACYP3A4NR4A2 | |
| SCHEMBL19251597 | 0.78 | OGA (0.39) | KDM4EMAPK1GCK | |
| SCHEMBL26664503 | 0.78 | GABRA1 (0.47) | KDM4EMAPK1DHODHGABRA1GABRB2 | |
| SCHEMBL13034790 | 0.78 | ALDH1A1 (0.53) | MAPK1RAB9AGABRA1GABRB2CYP3A4 | |
| SCHEMBL1006427 | 0.77 | TLR7 (0.43) | DHODHHTR2AHTR2CHTR2BPARP14 | |
| SCHEMBL13369864 | 0.77 | KDM4E (0.42) | KDM4EMAPTRAB9ACYP3A4 | |
| SCHEMBL23420994 | 0.75 | NR4A2 (0.51) | KDM4EMAPK1GABRA1GABRB2NR4A2 | |
| SCHEMBL113636 | 0.74 | ALDH1A1 (0.53) | KDM4EMAPTRAB9AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512478-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | Novartis AG (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011084549-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2011-07-14 | — | — | WO | disclosed |