SCHEMBL22315536

SCHEMBL22315536

c1ccc2cc3c(cc2c1)c1cc2ccccc2cc1n3-c1cc(-c2nc(-c3cccc4ccccc34)nc(-c3cccc4oc5ccccc5c34)n2)c2oc3ccccc3c2c1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.33
PRKDC P78527 2/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25048856 0.97 ALOX5 (0.32) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL24382028 0.94 ALOX5 (0.33) ALOX5PRKDCPIK3CDPIK3CBALDH1A1
SCHEMBL22311319 0.93 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBKDM4E
SCHEMBL23736733 0.92 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CBKDM4E
SCHEMBL23736504 0.91 ALOX5 (0.32) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL22311701 0.90 ALOX5 (0.36) ALOX5PRKDCPIK3CDPIK3CBKDM4E
SCHEMBL24382591 0.90 ALOX5 (0.36) ALOX5PRKDCPIK3CDPIK3CBKDM4E
SCHEMBL23737744 0.89 ALOX5 (0.32) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL25051415 0.89 ALOX5 (0.33) ALOX5PRKDCPIK3CDPIK3CBKDM4E
SCHEMBL25051263 0.89 ALOX5 (0.33) ALOX5PRKDCPIK3CDPIK3CBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230049674-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-02-16 US disclosed
EP-3863077-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2022-05-04 EP disclosed
EP-3863077-A1 ORGANIC LIGHT EMITTING DIODE LG Chem, Ltd. (KR) 2021-08-11 EP disclosed
WO-2020159333-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2020-08-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230049674-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, ELOVL1, CRY1 ALOX5 642/4885PRKDC 3901/4885PIK3CD 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.