Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22316972 | 0.82 | CYP4F2 (0.40) | — | |
| SCHEMBL15875664 | 0.76 | HCAR2 (0.32) | POLBNPSR1 | |
| SCHEMBL22315716 | 0.71 | APLNR (0.31) | LMNA | |
| SCHEMBL22316960 | 0.71 | APLNR (0.31) | LMNA | |
| SCHEMBL16672492 | 0.71 | TDP1 (0.44) | TDP1LMNA | |
| SCHEMBL22445923 | 0.68 | POLB (0.33) | POLBKMT2A | |
| SCHEMBL30874619 | 0.67 | NOS1 (0.35) | — | |
| SCHEMBL21877017 | 0.67 | CA12 (0.33) | POLBNPSR1TDP1 | |
| SCHEMBL29283271 | 0.66 | TDP1 (0.33) | POLBNPSR1TDP1LMNAKMT2A | |
| SCHEMBL31638119 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518101-B | Pyrrolopyrimidine derivatives and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-29 | — | — | CN | disclosed |
| EP-3919498-A1 | PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2021-12-08 | — | — | EP | disclosed |
| CN-111518101-A | Pyrrolopyrimidine derivatives and uses thereof | 湖北生物医药产业技术研究院有限公司 | 2020-08-11 | — | — | CN | disclosed |
| WO-2020156459-A1 | PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF | 湖北生物医药产业技术研究院有限公司 | 2020-08-06 | — | — | WO | disclosed |