Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19823464 | 0.82 | SMN1; SMN2 (0.34) | TDP1KDM4EALDH1A1POLBCYP2D6 | |
| SCHEMBL19823462 | 0.82 | SMN1; SMN2 (0.34) | TDP1KDM4EALDH1A1POLBCYP2D6 | |
| SCHEMBL21877017 | 0.77 | CA12 (0.33) | TDP1CA1CA2CA7CA12 | |
| SCHEMBL30874619 | 0.77 | NOS1 (0.35) | CA1CA2CA7CA12APLNR | |
| SCHEMBL1696184 | 0.76 | MEN1 (0.38) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL29283258 | 0.75 | MAOA (0.38) | TDP1CA1CA2ALDH1A1CA7 | |
| SCHEMBL26888163 | 0.75 | ALDH1A1 (0.41) | CA1CA2ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL28883407 | 0.74 | MEN1 (0.31) | CA1CA2KMT2AMEN1GAA | |
| SCHEMBL30068345 | 0.74 | CA1 (0.35) | CA1CA2ALDH1A1CA7KMT2A | |
| SCHEMBL29283275 | 0.73 | SLC6A5 (0.37) | CA1CA2KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103074-A | Cytotoxic targeting chimeras for CCR2 expressing cells | 葛兰素史克知识产权发展有限公司 | 2024-05-28 | — | — | CN | disclosed |