Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402975 | 0.91 | HDAC3 (0.50) | ALDH1A1MAPK1CYP3A4TSHRTDP1 | |
| SCHEMBL11245458 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPK1CYP3A4TSHRTDP1 | |
| SCHEMBL27421351 | 0.81 | LMNA (0.48) | MAPK1CYP3A4L3MBTL1LMNASCN5A | |
| SCHEMBL11237791 | 0.81 | HPGD (0.53) | ALDH1A1TDP1KMT2AHDAC3HDAC1 | |
| SCHEMBL11235830 | 0.81 | HPGD (0.53) | ALDH1A1TDP1KMT2AHDAC3HDAC1 | |
| SCHEMBL11236735 | 0.81 | HPGD (0.53) | ALDH1A1TDP1KMT2AHDAC3HDAC1 | |
| SCHEMBL11236862 | 0.81 | HPGD (0.53) | ALDH1A1TDP1KMT2AHDAC3HDAC1 | |
| SCHEMBL11742439 | 0.80 | LMNA (0.47) | ALDH1A1MAPK1CYP3A4LMNASCN5A | |
| SCHEMBL23072450 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MAPK1L3MBTL1RAB9AKMT2A | |
| SCHEMBL1836932 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MAPK1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200247845-A1 | Hemiasterlin Derivatives and Antibody-Drug Conjugates Including Same | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247845-A1 | Hemiasterlin Derivatives and Antibody-Drug Conjugates Including Same | FCGRT, QARS1, INHA | ALDH1A1 1215/4885MAPK1 3449/4885CYP3A4 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.