SCHEMBL22318985

SCHEMBL22318985

O=C(O)Nc1ccc(S(=O)(=O)Nc2c(Cl)cccc2Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR27 Q9NS67 10/20 0.54
ATM Q13315 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
GAA P10253 2/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
GFER P55789 1/20 0.50
ALDH1A1 P00352 1/20 0.50
PCTP Q9UKL6 1/20 0.49
STARD10 Q9Y365 1/20 0.49
AVPR2 P30518 1/20 0.49
ADRA2B P18089 1/20 0.49
TP53 P04637 1/20 0.49
POLB P06746 1/20 0.49
GRM4 Q14833 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19329469 0.77 MEN1 (0.73) MEN1KMT2AGAAMAPTGFER
SCHEMBL7824876 0.77 ACLY (0.58) MEN1KMT2AGAALMNA
SCHEMBL22318984 0.76 GAA (0.65) MEN1KMT2AGAALMNAMAPT
SCHEMBL6862639 0.76 TP53 (0.59) GPR27MEN1KMT2AAVPR2TP53
SCHEMBL25372776 0.76 KMT2A (0.62) GPR27MEN1KMT2ALMNAMAPT
SCHEMBL17507344 0.74 GAA (0.55) GPR27MEN1KMT2AGAALMNA
SCHEMBL6351422 0.74 HTT (0.67) GPR27ATMMEN1KMT2AGAA
SCHEMBL27420456 0.73 ERBB2 (0.56) MEN1KMT2AGAAMAPTGFER
SCHEMBL15779688 0.73 ALDH1A1 (0.59) MEN1KMT2AGAALMNAMAPT
SCHEMBL6646221 0.72 PCTP (0.69) LMNANPSR1ALDH1A1PCTPSTARD10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3351530-B1 METHOD OF PRODUCING A SODIUM SALT OF (2,6-DICHLOROPHENYL)AMIDE CARBOPENTOXYSULPHANILIC ACID TETS VIKTOR VENIAMINOVICH (RU) 2020-08-12 EP claimed