Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.58 |
| ▸ | METAP2 | P50579 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | CCR9 | P51686 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552241 | 0.80 | TSHR (0.50) | ACLYMEN1KMT2ALMNACCR9 | |
| SCHEMBL15779688 | 0.80 | ALDH1A1 (0.59) | GAAMEN1KMT2ALMNAFFAR4 | |
| SCHEMBL12200963 | 0.80 | ACLY (0.78) | ACLYMETAP2MEN1KMT2ALMNA | |
| SCHEMBL28930113 | 0.78 | METAP2 (0.62) | ACLYMETAP2GAAMEN1KMT2A | |
| SCHEMBL1688339 | 0.78 | METAP2 (0.71) | METAP2MEN1KMT2ALMNAFFAR4 | |
| SCHEMBL22318985 | 0.77 | GPR27 (0.54) | GAAMEN1KMT2ALMNA | |
| SCHEMBL5326630 | 0.76 | ACLY (0.72) | ACLYMETAP2GAAMEN1KMT2A | |
| SCHEMBL5839080 | 0.75 | AR (0.57) | METAP2MEN1KMT2ALMNAFFAR4 | |
| SCHEMBL9864681 | 0.75 | METAP2 (0.58) | ACLYMETAP2MEN1KMT2AMCL1 | |
| SCHEMBL7308406 | 0.74 | TSHR (0.59) | ACLYMEN1KMT2ALMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |