Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8266974 | 0.83 | IMPDH2 (0.61) | IMPDH2ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL31106988 | 0.83 | IMPDH2 (0.61) | IMPDH2ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL16473786 | 0.75 | IMPDH2 (0.50) | IMPDH2ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL30041728 | 0.73 | IMPDH2 (0.51) | IMPDH2ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL1254742 | 0.73 | IMPDH2 (0.51) | IMPDH2ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL1778037 | 0.71 | IMPDH2 (1.00) | IMPDH2ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL30344324 | 0.71 | IMPDH2 (1.00) | IMPDH2ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL579481 | 0.70 | IMPDH2 (0.56) | IMPDH2ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL3980032 | 0.67 | IMPDH2 (0.61) | IMPDH2ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL6922436 | 0.67 | IMPDH2 (0.61) | IMPDH2ALDH1A1SMN1; SMN2KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11629138-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| EP-3692029-B1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-12 | — | — | EP | disclosed |
| US-20200255400-A1 | Microbiocidal Picolinamide Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255400-A1 | Microbiocidal Picolinamide Derivatives | PRF1, CASP1, FPR1 | IMPDH2 882/4885ALDH1A1 1067/4885SMN1; SMN2 3397/4885 |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, FPR1 | IMPDH2 882/4885ALDH1A1 1067/4885SMN1; SMN2 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.