Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8266974 | 1.00 | IMPDH2 (0.61) | IMPDH2ALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL22320202 | 0.83 | IMPDH2 (0.54) | IMPDH2ALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL16473786 | 0.80 | IMPDH2 (0.50) | IMPDH2ALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL1254742 | 0.78 | IMPDH2 (0.51) | IMPDH2ALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL30041728 | 0.78 | IMPDH2 (0.51) | IMPDH2ALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL24853984 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2XDHLMNAGAA | |
| SCHEMBL28592975 | 0.77 | XDH (0.45) | IMPDH2ALDH1A1XDHLMNA | |
| SCHEMBL30173392 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2XDHLMNAGAA | |
| SCHEMBL10095261 | 0.77 | XDH (0.43) | IMPDH2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30173391 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2XDHLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240293331-A1 | ORAL FORMULATION CONTAINING 1-(3-CYANO-1-ISOPROPYL-INDOL-5-YL)PYRAZOLE-4-CARBOXYLIC ACID | LG CHEM, LTD. (KR) | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240293331-A1 | ORAL FORMULATION CONTAINING 1-(3-CYANO-1-ISOPROPYL-INDOL-5-YL)PYRAZOLE-4-CARBOXYLIC ACID | PGA5, IDO1, CYP3A5 | IMPDH2 64/4885ALDH1A1 1287/4885SMN1; SMN2 3682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.