Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397067 | 1.00 | BLM (0.41) | BLMLMNAMEN1HBBKMT2A | |
| SCHEMBL4736289 | 0.88 | TSHR (0.44) | BLMLMNAMEN1HBBKMT2A | |
| SCHEMBL457977 | 0.87 | — | — | |
| Methane SCHEMBL2013838 | 0.85 | LMNA (0.46) | BLMLMNAMEN1HBBKMT2A | |
| SCHEMBL4735665 | 0.83 | BLM (0.33) | BLMLMNAMEN1HBBKMT2A | |
| Ethane SCHEMBL2012063 | 0.83 | LMNA (0.44) | BLMLMNAMEN1HBBKMT2A | |
| SCHEMBL439675 | 0.82 | ALDH1A1 (0.46) | ALDH1A1PTGS1PTGS2CA12CA1 | |
| SCHEMBL11792981 | 0.82 | ALDH1A1 (0.46) | ALDH1A1PTGS1PTGS2CA12CA1 | |
| SCHEMBL437092 | 0.82 | ALDH1A1 (0.46) | ALDH1A1PTGS1PTGS2CA12CA1 | |
| SCHEMBL28277555 | 0.82 | ALDH1A1 (0.46) | ALDH1A1PTGS1PTGS2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108843-A1 | USE OF NITROOXYDERIVATIVE OF PARACETAMOL FOR THE TREATMENT OF MUSCULAR DYSTROPHIES | NICOX S.A. (FR) | 2010-09-30 | — | — | WO | claimed |
| EP-2229161-A2 | COMPOSITION COMPRISING A NITROOXYDERIVATIVE OF ACETAMINOPHEN AND A ANTICONVULSANT DRUG FOR THE TREATMENT OF NEUROPATHIC PAIN | Nicox S.A. (FR) | 2010-09-22 | — | — | EP | claimed |
| WO-2009087005-A2 | COMPOSITION COMPRISING A NITROOXYDERIVATIVE OF ACETAMINOPHEN AND A ANTICONVULSANT DRUG FOR THE TREATMENT OF NEUROPATHIC PAIN | NICOX S.A. (FR) | 2009-07-16 | — | — | WO | claimed |
| WO-2011101245-A1 | NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPATHIC PAIN | NICOX S.A. (FR) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011092065-A1 | NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPHATIC PAIN | NICOX S.A. (FR) | 2011-08-04 | — | — | WO | disclosed |
| WO-2010108843-A1 | USE OF NITROOXYDERIVATIVE OF PARACETAMOL FOR THE TREATMENT OF MUSCULAR DYSTROPHIES | NICOX S.A. (FR) | 2010-09-30 | — | — | WO | disclosed |