Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.53 |
| ▸ | TRPV3 | Q8NET8 | 12/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22321585 | 1.00 | SCN9A (0.53) | SCN9ATRPV3 | |
| SCHEMBL22321659 | 1.00 | SCN9A (0.53) | SCN9ATRPV3 | |
| SCHEMBL22337695 | 0.84 | TRPV3 (0.52) | SCN9ATRPV3 | |
| SCHEMBL22321581 | 0.80 | TRPV3 (0.42) | SCN9ATRPV3 | |
| SCHEMBL22321580 | 0.80 | TRPV3 (0.42) | SCN9ATRPV3 | |
| SCHEMBL22321632 | 0.80 | TRPV3 (0.42) | SCN9ATRPV3 | |
| SCHEMBL22321594 | 0.78 | TRPV3 (0.39) | SCN9ATRPV3 | |
| SCHEMBL22321597 | 0.78 | TRPV3 (0.39) | SCN9ATRPV3 | |
| SCHEMBL22321569 | 0.78 | KCNH2 (0.44) | SCN9ATRPV3 | |
| SCHEMBL22321627 | 0.73 | KIF11 (0.47) | SCN9ATRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11220482-B2 | Aminopyridinemethanol compounds and their use | UNIVERSITE AMIENS PICARDIE JULES VERNE (FR) | 2022-01-11 | — | — | US | disclosed |
| US-11220482-B2 | Aminopyridinemethanol compounds and their use | UNIVERSITE AMIENS PICARDIE JULES VERNE (FR) | 2022-01-11 | — | — | US | disclosed |
| EP-3704093-A1 | NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE | Université Amiens Picardie Jules Verne (FR) | 2020-09-09 | — | — | EP | disclosed |
| US-20200255379-A1 | NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE | UNIV AMIENS PICARDIE JULES VERNE (FR) | 2020-08-13 | — | — | US | disclosed |
| US-20200255379-A1 | NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE | UNIV AMIENS PICARDIE JULES VERNE (FR) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11220482-B2 | Aminopyridinemethanol compounds and their use | QDPR, PNMT, CYP3A43 | SCN9A 1397/4885TRPV3 221/4885 |
| US-20200255379-A1 | NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE | QDPR, PNMT, CYP3A43 | SCN9A 1141/4885TRPV3 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.