Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784589 | 0.83 | KDM4E (0.42) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16321040 | 0.81 | KDM4E (0.40) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4319170 | 0.79 | MEN1 (0.47) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL30332910 | 0.76 | ALOX5 (0.43) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3084911 | 0.75 | LTA4H (0.47) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| Hydrogen Sulfide SCHEMBL27738387 | 0.74 | ALOX5 (0.42) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| Pyrrole SCHEMBL28809703 | 0.74 | MEN1 (0.39) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL27510656 | 0.74 | LTA4H (0.53) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| Hydrogen Sulfide SCHEMBL27605763 | 0.74 | LTA4H (0.46) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1487707 | 0.73 | ALOX5 (0.39) | HPGDKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356709-A1 | OPTOELECTRONIC DEVICES | Cambridge Enterprise Ltd. (GB) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010064028-A1 | OPTOELECTRONIC DEVICES | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2010-06-10 | — | — | WO | disclosed |