Pyrrole

Pyrrole

SCHEMBL28809703

c1cc[nH]c1.c1ccc(-c2c(-c3cccs3)sc(-c3cccs3)c2-c2ccccc2)cc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
KDM4E B2RXH2 5/20 0.39
ALDH1A1 P00352 3/20 0.39
MAPT P10636 3/20 0.39
PPARG P37231 2/20 0.39
NCOA2 Q15596 2/20 0.39
NCOA1 Q15788 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
HPGD P15428 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38
ALOX5 P09917 1/20 0.38
DPP4 P27487 1/20 0.37
LTA4H P09960 2/20 0.36
CYP2E1 P05181 1/20 0.36
CYP2A6 P11509 1/20 0.36
CYP2B6 P20813 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2784589 0.83 KDM4E (0.42) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL16321040 0.80 KDM4E (0.40) MEN1KMT2AKDM4EALDH1A1MAPT
Pyrrole SCHEMBL28839158 0.75 DPP4 (0.50) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL2232263 0.74 HPGD (0.38) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL28825683 0.74 KDM4E (0.36) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL4319170 0.73 MEN1 (0.47) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL28399939 0.69 ALOX5 (0.42) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL31124 0.69 CYP3A4 (0.58) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL27891520 0.68 ALOX5 (0.48) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL29177041 0.68 SLC6A11 (0.41) MEN1KMT2AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103435784-A Benzodithiophene-like polymer as well as preparation method and application thereof NANJING YOUSIBEITE PHOTOELECTRIC MATERIAL CO LTD 2013-12-11 CN disclosed