SCHEMBL2784589

SCHEMBL2784589

c1ccc(-c2sc(-c3cccs3)c(-c3cccs3)c2-c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.42
MAPT P10636 4/20 0.42
CYP3A4 P08684 3/20 0.42
CYP2C9 P11712 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP2D6 P10635 1/20 0.42
ALOX5 P09917 1/20 0.39
CYP2E1 P05181 1/20 0.38
CYP2A6 P11509 1/20 0.38
CYP2B6 P20813 1/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 1/20 0.38
PPARG P37231 2/20 0.37
NCOA2 Q15596 2/20 0.37
NCOA1 Q15788 2/20 0.37
ACHE P22303 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16321040 0.97 KDM4E (0.40) KDM4EMAPTCYP3A4CYP2C9CYP1A2
SCHEMBL4319170 0.84 MEN1 (0.47) KDM4EMAPTCYP3A4CYP2C9CYP1A2
SCHEMBL2232263 0.83 HPGD (0.38) KDM4EMAPTCYP3A4CYP2C9CYP1A2
Pyrrole SCHEMBL28809703 0.83 MEN1 (0.39) KDM4EMAPTCYP3A4CYP2C9CYP1A2
SCHEMBL1224397 0.78 MAPT (0.56) KDM4EMAPTCYP3A4CYP2C9CYP1A2
SCHEMBL28825683 0.73 KDM4E (0.36) KDM4EMAPTCYP3A4CYP2C9CYP1A2
SCHEMBL22899959 0.73 ACHE (0.53) KDM4EMAPTCYP3A4CYP2C9CYP1A2
SCHEMBL4585406 0.72 MEN1 (0.41) KDM4EMAPTCYP3A4CYP2C9CYP2E1
SCHEMBL4585875 0.72 MEN1 (0.41) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL302311 0.71 MEN1 (0.38) KDM4EMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2518075-B1 INDUCED LAYER MATERIAL FOR PREPARING NON-PLANAR METAL PHTHALOCYANINE WEAK EPITAXY GROWTH THIN FILM CHANGCHUN FLEXIBLE DISPLAY TECHNOLOGY CO LTD (CN) 2015-07-08 EP disclosed
EP-2254727-A2 METHOD OF THERMOCLEAVING A POLYMER LAYER The Technical University of Denmark (DTU) (DK) 2010-12-01 EP disclosed
EP-2253034-A1 AIR STABLE PHOTOVOLTAIC DEVICE The Technical University of Denmark (DTU) (DK) 2010-11-24 EP disclosed
WO-2009130164-A2 PHOTOVOLTAIC DEVICE THE TECHNICAL UNIVERSITY OF DENMARK (DK) 2009-10-29 WO disclosed
WO-2009103706-A2 METHOD OF THERMOCLEAVING A POLYMER LAYER THE TECHNICAL UNIVERSITY OF DENMARK (DK) 2009-08-27 WO disclosed
WO-2009103705-A1 AIR STABLE PHOTOVOLTAIC DEVICE THE TECHNICAL UNIVERSITY OF DENMARK (DK) 2009-08-27 WO disclosed