SCHEMBL22323741

SCHEMBL22323741

CC(C)(C)[Si](C)(C)Oc1ccc(CBr)cc1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.46
CA2 P00918 1/20 0.34
CA12 O43570 4/20 0.34
CA1 P00915 4/20 0.34
CA9 Q16790 4/20 0.34
PREP P48147 1/20 0.32
SHBG P04278 2/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
ALDH1A1 P00352 2/20 0.30
HPGD P15428 1/20 0.30
PPARG P37231 1/20 0.30
PPARD Q03181 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1635299 0.93 DRD2 (0.51) DRD2CA2CA12CA1CA9
SCHEMBL9959203 0.89 DRD2 (0.47) DRD2LMNASMN1; SMN2ALDH1A1
SCHEMBL3960531 0.86 CYP4F2 (0.40) DRD2CA12CA1CA9CYP4F2
SCHEMBL29594393 0.86 KMT2A (0.41) DRD2SMN1; SMN2CYP4F2CYP4A11ALDH1A1
SCHEMBL9128692 0.86 KMT2A (0.41) DRD2SMN1; SMN2CYP4F2CYP4A11ALDH1A1
SCHEMBL7261819 0.86 DRD2 (0.40) DRD2CA12CA1CA9LMNA
SCHEMBL9040112 0.86 DRD2 (0.44) DRD2CA2CA12CA1CA9
SCHEMBL30008548 0.85 MEN1 (0.44) LMNAKDM4EALDH1A1
SCHEMBL28706045 0.84 DRD2 (0.39) DRD2PPARGPPARDPPARA
SCHEMBL22068058 0.83 DRD2 (0.45) DRD2CA2CYP4F2CYP4A11KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220109157-A1 Conducting redox oligomers SJOEDIN MARTIN (SE) 2022-04-07 US disclosed
EP-3921359-A1 CONDUCTING REDOX OLIGOMERS Sjödin, Martin (SE) 2021-12-15 EP disclosed
WO-2020162824-A1 CONDUCTING REDOX OLIGOMERS SJÖDIN MARTIN (SE) 2020-08-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220109157-A1 Conducting redox oligomers NOX4, CYBB, LPO DRD2 2405/4885CA2 1509/4885CA12 1461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.