Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888975 | 0.88 | RAB9A (0.45) | MEN1KMT2ANPC1RAB9AFFAR4 | |
| SCHEMBL22323741 | 0.85 | DRD2 (0.46) | KDM4EALDH1A1LMNA | |
| SCHEMBL14511787 | 0.85 | PTGER1 (0.45) | KDM4EFFAR4HSD17B10ALDH1A1MAPT | |
| SCHEMBL14511752 | 0.85 | SLC6A4 (0.52) | RAB9ACYP1A2ALDH1A1LMNA | |
| SCHEMBL3236287 | 0.82 | SLC2A1 (0.52) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL6449283 | 0.82 | CCR5 (0.51) | RAB9ACYP1A2ALDH1A1LMNA | |
| SCHEMBL1107091 | 0.82 | PTGER1 (0.45) | FFAR4MAPTLMNAMAPK1 | |
| SCHEMBL22621079 | 0.81 | MEN1 (0.44) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL28888981 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL14511751 | 0.81 | LIPE (0.47) | NPC1RAB9AKDM4ECYP1A2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059219-A1 | LIGNAN DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2025-02-20 | — | — | US | disclosed |
| CN-117440947-A | Lignan derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2024-01-23 | — | — | CN | disclosed |
| WO-2022222686-A1 | LIGNAN DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2022-10-27 | — | — | WO | disclosed |
| CN-115215821-A | Lignan derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2022-10-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059219-A1 | LIGNAN DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | HADHA, HADHB, HADH | MEN1 2640/4885KMT2A 4107/4885NPC1 1672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.