Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | PHGDH | O43175 | 1/20 | 0.59 |
| ▸ | MGLL | Q99685 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848450 | 0.80 | FAAH (0.64) | ALDH1A1FAAHPHGDHMGLLCA12 | |
| SCHEMBL25137386 | 0.80 | FAAH (0.64) | ALDH1A1FAAHPHGDHMGLLCA12 | |
| Quinoline SCHEMBL29113186 | 0.80 | ALDH1A1 (0.52) | ALDH1A1FAAHPHGDHMGLLCA12 | |
| SCHEMBL11692693 | 0.79 | ALDH1A1 (0.48) | ALDH1A1FAAHPHGDHMGLLCA12 | |
| SCHEMBL25920874 | 0.79 | ALDH1A1 (0.42) | ALDH1A1FAAHPHGDHMGLLCA12 | |
| SCHEMBL25920887 | 0.79 | ALDH1A1 (0.52) | ALDH1A1FAAHPHGDHMGLLCA12 | |
| SCHEMBL5961342 | 0.78 | FAAH (0.61) | ALDH1A1FAAHPHGDHMGLLCA12 | |
| SCHEMBL2979996 | 0.77 | KMT2A (0.44) | ALDH1A1FAAHPHGDHMGLLCA12 | |
| SCHEMBL11371559 | 0.77 | ALDH1A1 (0.40) | ALDH1A1FAAHPHGDHMGLLCA12 | |
| SCHEMBL8661742 | 0.77 | FAAH (0.55) | ALDH1A1FAAHPHGDHMGLLCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115449136-B | Accelerator composition of rubber nanocomposite as well as preparation method and application thereof | 浙江大学 | 2024-02-27 | — | — | CN | claimed |
| CN-115125593-B | Application of chelating agent in PCB preparation | 生益电子股份有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-116731654-A | Low-temperature quick-curing epoxy adhesive and preparation method thereof | 成都拓利科技股份有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-115449136-A | Accelerator composition of rubber nanocomposite and preparation method and application thereof | 浙江大学 | 2022-12-09 | — | — | CN | claimed |
| CN-115125593-A | Application of chelating agent in PCB preparation | 生益电子股份有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-107486140-A | Attapulgite adsorbing material for solidifying chromium in river bottom mud and preparation method thereof | 北京清水润土环保科技有限公司 | 2017-12-19 | — | — | CN | claimed |
| CN-1291981-C | Method for preparing 3-methyl-2-benzothiazolinone hydrazone and its hydrochloride | UNIV FUDAN (CN) | 2006-12-27 | — | — | CN | claimed |
| US-7153411-B2 | Method for cleaning and polishing metallic alloys and articles cleaned or polished thereby | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2006-12-26 | — | — | US | claimed |
| CN-1634900-A | Method for preparing 3-methyl-2-benzothiazolinone hydrazone and its hydrochloride | UNIV FUDAN (CN) | 2005-07-06 | — | — | CN | claimed |
| US-20040192930-A1 | Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2004-09-30 | — | — | US | claimed |
| EP-0923933-B1 | Substituted pyrazolyl benzenesulfonamides for use in the treatment of inflammation | SEARLE & CO (US) | 2002-07-03 | — | — | EP | claimed |
| EP-0923933-A1 | Substituted pyrazolyl benzenesulfonamides for use in the treatment of inflammation | G.D. SEARLE & CO. (US) | 1999-06-23 | — | — | EP | claimed |
| EP-0854723-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR USE IN VETERINARY THERAPIES AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1998-07-29 | — | — | EP | claimed |
| WO-1997011704-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR USE IN VETERINARY THERAPIES AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1997-04-03 | — | — | WO | claimed |
| EP-0731795-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-09-18 | — | — | EP | claimed |
| WO-1995015316-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR THE TREATMENT OF INFLAMMATION | G. D. SEARLE & CO. (US) | 1995-06-08 | — | — | WO | claimed |
| CN-115449136-B | Accelerator composition of rubber nanocomposite as well as preparation method and application thereof | 浙江大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-115125593-B | Application of chelating agent in PCB preparation | 生益电子股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-4252963-A | CYCLIZATION OF PHENYLTHIOUREAS WITH THIONYL CHLORIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
| US-4113732-A | CATALYTIC OXIDATIVE CYCLIZATION, CHLORINE AS OXIDIZER | BASF AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192930-A1 | Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation | IL6, HRH4, CCR2 | ALDH1A1 1964/4885FAAH 301/4885PHGDH 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.