Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 16/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20590806 | 0.83 | NPC1 (0.54) | ALKBH1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL4667925 | 0.81 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL30723585 | 0.79 | ALKBH1 (0.50) | ALKBH1SMN1; SMN2 | |
| SCHEMBL1186530 | 0.78 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL875608 | 0.73 | LMNA (0.53) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL15952657 | 0.71 | KIT (0.54) | ALKBH1NPC1RAB9ASMN1; SMN2P4HTM | |
| SCHEMBL3235402 | 0.71 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL30212486 | 0.70 | KCNH2 (0.47) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL22325535 | 0.70 | CYP2A6 (0.40) | SMN1; SMN2LMNAMAPT | |
| SCHEMBL15953346 | 0.70 | KIT (0.53) | ALKBH1NPC1RAB9ASMN1; SMN2P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162612-A1 | PYRIDINE COMPOUND SUBSTITUTED BY HETEROARYL | 大正製薬株式会社 | 2020-08-13 | — | — | WO | disclosed |