Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921059 | 0.82 | CYP1A2 (0.38) | SMN1; SMN2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL24921660 | 0.80 | CYP1A2 (0.38) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL30212206 | 0.79 | KCNH2 (0.54) | KCNH2CYSLTR2CYSLTR1NPC1RAB9A | |
| SCHEMBL30212372 | 0.77 | KCNH2 (0.49) | KCNH2CYSLTR2CYSLTR1NPC1RAB9A | |
| SCHEMBL22325530 | 0.70 | ALKBH1 (0.56) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL3625207 | 0.70 | CYP2A6 (0.41) | SMN1; SMN2LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL4667925 | 0.69 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL20746692 | 0.68 | KCNH2 (0.61) | KCNH2CYSLTR2CYSLTR1NPC1RAB9A | |
| SCHEMBL2666365 | 0.68 | CYP2A6 (0.40) | SMN1; SMN2LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL17898216 | 0.68 | KCNH2 (0.61) | KCNH2CYSLTR2CYSLTR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |