Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.37 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391147 | 0.89 | HSD11B1 (0.44) | HSD11B1OPRM1KMT2AMEN1AKR1C1 | |
| SCHEMBL3393922 | 0.88 | MEN1 (0.47) | HSD11B1OPRM1KMT2AMEN1AKR1C1 | |
| SCHEMBL27993675 | 0.78 | SIGMAR1 (0.39) | HSD11B1OPRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL20854804 | 0.77 | CHRM5 (0.34) | — | |
| SCHEMBL28536867 | 0.77 | MEN1 (0.47) | HSD11B1OPRM1KMT2AMEN1AKR1C1 | |
| SCHEMBL3433975 | 0.76 | MEN1 (0.46) | HSD11B1OPRM1KMT2AMEN1AKR1C1 | |
| SCHEMBL27197448 | 0.76 | HSD11B1 (0.38) | HSD11B1OPRM1KMT2AMEN1AKR1C1 | |
| SCHEMBL21683014 | 0.75 | HSD11B1 (0.39) | HSD11B1KMT2AMEN1CYP2D6SMN1; SMN2 | |
| SCHEMBL21683027 | 0.74 | HSD11B1 (0.41) | HSD11B1KMT2AMEN1CYP2D6SMN1; SMN2 | |
| SCHEMBL10322683 | 0.70 | OPRM1 (0.47) | HSD11B1OPRM1KMT2AMEN1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |