Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 6/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174432 | 0.91 | ACACA (0.39) | ACACAMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL20174311 | 0.83 | MAPT (0.38) | MAPK1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL20174437 | 0.81 | ACACA (0.38) | ACACAMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL20174424 | 0.79 | ACACA (0.38) | ACACAMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL20174396 | 0.78 | KMT2A (0.35) | MAPK1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL20174314 | 0.78 | ALDH1A1 (0.36) | MAPK1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL22326574 | 0.78 | ENPP3 (0.34) | MAPK1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL20174315 | 0.77 | ENPP3 (0.35) | ACACAMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL20174724 | 0.77 | PDK2 (0.33) | ACACAMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL20174390 | 0.77 | CYP1A1 (0.40) | ACACAMAPK1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | LG CHEM, LTD. (KR) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | CRY1, NR2E3, ERG | ACACA 2815/4885HDAC6 2215/4885MAPK1 3742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.