SCHEMBL22326593

SCHEMBL22326593

Cc1ccc([Si](C)(C)c2ccc(C)c(CCc3cc([Si](C)(C)c4ccc(C)c(C)c4)ccc3C)c2)cc1C

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.38
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32
AR P10275 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822287 0.85 ALDH1A1 (0.42) ESR1ESR2ARALDH1A1POLB
SCHEMBL12792105 0.77 TDP1 (0.36) ESR1ESR2ARALDH1A1
SCHEMBL10007491 0.75 ESR1 (0.54) ESR1ESR2ALDH1A1POLB
SCHEMBL11947073 0.75 ALDH1A1 (0.39) ESR1ESR2ARALDH1A1
SCHEMBL26434258 0.75
SCHEMBL21712673 0.75
SCHEMBL12792120 0.72 ACHE (0.42) ESR1ESR2ALDH1A1
SCHEMBL3313456 0.71 ALDH1A1 (0.42) ESR1ESR2ARALDH1A1POLB
SCHEMBL9359937 0.69 RAB9A (0.36) ALDH1A1
SCHEMBL3824007 0.69 ALDH1A1 (0.40) ESR1ESR2ARALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10738164-B2 Poly(amide-imide) copolymer, method of manufacturing the same, poly(amide-imide) copolymer film, window for display device, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-08-11 US disclosed