SCHEMBL822287

SCHEMBL822287

Cc1ccc([Si](C)(C)c2ccc(C)c(C)c2)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
ESR1 P03372 3/20 0.36
ESR2 Q92731 3/20 0.36
HPGD P15428 1/20 0.36
AR P10275 2/20 0.35
TDP1 Q9NUW8 2/20 0.34
TSHR P16473 2/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
LMNA P02545 1/20 0.34
NOTUM Q6P988 2/20 0.34
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
NQO2 P16083 1/20 0.33
ACHE P22303 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12792105 0.91 TDP1 (0.36) ALDH1A1ESR1ESR2HPGDAR
SCHEMBL10007491 0.89 ESR1 (0.54) ALDH1A1ESR1ESR2HPGDTSHR
SCHEMBL11947073 0.89 ALDH1A1 (0.39) ALDH1A1ESR1ESR2HPGDAR
SCHEMBL12792120 0.85 ACHE (0.42) ALDH1A1ESR1ESR2HPGDTDP1
SCHEMBL22326593 0.85 TAAR1 (0.38) ALDH1A1ESR1ESR2ARPOLB
SCHEMBL3313456 0.83 ALDH1A1 (0.42) ALDH1A1ESR1ESR2ARTDP1
SCHEMBL9359937 0.82 RAB9A (0.36) ALDH1A1MAPTRAB9A
SCHEMBL3824007 0.81 ALDH1A1 (0.40) ALDH1A1ESR1ESR2ARTDP1
SCHEMBL1313523 0.79 ALDH1A1 (0.39) ALDH1A1ESR1ESR2ARTDP1
SCHEMBL1314576 0.79 ALDH1A1 (0.39) ALDH1A1ESR1ESR2ARTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111234218-A Preparation method of soluble polyimide containing amino phenylsulfonyl hexafluoropropane structure 桂林理工大学 2020-06-05 CN claimed
US-4940810-A OXIDATION OF DIALKYLDIARYLSILANE AMOCO CORPORATION (US) 1990-07-10 US claimed
US-11814483-B2 Separation membrane comprising coating layer, method of preparing same, and battery using same SAMSUNG SDI CO., LTD. (KR) 2023-11-14 US disclosed
US-11814483-B2 Separation membrane comprising coating layer, method of preparing same, and battery using same SAMSUNG SDI CO., LTD. (KR) 2023-11-14 US disclosed
US-20230357505-A1 POLY(AMIDE-IMIDE) COPOLYMER, METHOD OF MANUFACTURING THE SAME, POLY(AMIDE-IMIDE) COPOLYMER FILM, WINDOW FOR DISPLAY DEVICE, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-09 US disclosed
US-20230357505-A1 POLY(AMIDE-IMIDE) COPOLYMER, METHOD OF MANUFACTURING THE SAME, POLY(AMIDE-IMIDE) COPOLYMER FILM, WINDOW FOR DISPLAY DEVICE, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-09 US disclosed
US-11739183-B2 Poly(amide-imide) copolymer, method of manufacturing the same, poly(amide-imide) copolymer film, window for display device, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-29 US disclosed
US-11739183-B2 Poly(amide-imide) copolymer, method of manufacturing the same, poly(amide-imide) copolymer film, window for display device, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-29 US disclosed
US-11640110-B2 Resin composition, method for producing heat-resistant resin film, and display device TORAY INDUSTRIES, INC. (JP) 2023-05-02 US disclosed
US-11640110-B2 Resin composition, method for producing heat-resistant resin film, and display device TORAY INDUSTRIES, INC. (JP) 2023-05-02 US disclosed
US-11319410-B2 Precursor for polyimide and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2022-05-03 US disclosed
US-8013103-B2 Polymer compounds and a preparation method thereof INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2011-09-06 US disclosed
US-20100292356-A1 PREPARATION METHOD OF POLYBENZIMIDAZOLE IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2010-11-18 US disclosed
US-20100099804-A1 POLYMER COMPOUNDS AND A PREPARATION METHOD THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2010-04-22 US disclosed
US-20090297850-A1 HOLLOW FIBER, DOPE COMPOSITION FOR FORMING HOLLOW FIBER, AND METHOD OF MAKING HOLLOW FIBER USING THE SAME IUCF-HYU(INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2009-12-03 US disclosed
US-20090286078-A1 POLYIMIDES DOPE COMPOSITION, PREPARATION METHOD OF HOLLOW FIBER USING THE SAME AND HOLLOW FIBER PREPARED THEREFROM INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-11-19 US disclosed
US-20090286904-A1 POLYAMIC ACIDS DOPE COMPOSITION, PREPARATION METHOD OF HOLLOW FIBER USING THE SAME AND HOLLOW FIBER PREPARED THEREFROM INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-11-19 US disclosed
US-20090282982-A1 HOLLOW FIBER, DOPE COMPOSITION FOR FORMING HOLLOW FIBER, AND METHOD OF PREPARING HOLLOW FIBER USING THE SAME IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2009-11-19 US disclosed
US-4940810-A OXIDATION OF DIALKYLDIARYLSILANE AMOCO CORPORATION (US) 1990-07-10 US disclosed
US-4940810-A OXIDATION OF DIALKYLDIARYLSILANE AMOCO CORPORATION (US) 1990-07-10 US disclosed