Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.30 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.30 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21036858 | 0.76 | GABRA1 (0.39) | GABRA1GABRB2MEN1KMT2APTGS2 | |
| SCHEMBL23665220 | 0.73 | GABRA1 (0.34) | GABRA1GABRB2POLB | |
| SCHEMBL18712039 | 0.68 | KEAP1 (0.41) | GABRA1GABRB2POLB | |
| SCHEMBL21037102 | 0.67 | TBXAS1 (0.50) | GABRA1GABRB2MEN1POLBMAPT | |
| SCHEMBL18711999 | 0.67 | MAPK1 (0.36) | GABRA1GABRB2CYP2C9 | |
| SCHEMBL17229324 | 0.66 | BRD4 (0.51) | POLBLMNATSHR | |
| SCHEMBL14518822 | 0.66 | CYP2A6 (0.46) | GABRA1GABRB2MEN1POLBMAPT | |
| SCHEMBL28045529 | 0.64 | GABRA1 (0.51) | GABRA1GABRB2MEN1POLBMAPT | |
| SCHEMBL5053439 | 0.64 | GABRA1 (0.62) | GABRA1GABRB2MEN1POLBMAPT | |
| SCHEMBL17877179 | 0.64 | GABRA1 (0.39) | GABRA1GABRB2MEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210221796-A1 | ANTIBACTERIAL COMPOUNDS | BLACKSMITH MEDICINES, INC. | 2021-07-22 | — | — | US | disclosed |
| US-11021471-B2 | Antibacterial compounds | FORGE THERAPEUTICS, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200255413-A1 | ANTIBACTERIAL COMPOUNDS | BLACKSMITH MEDICINES, INC. | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221796-A1 | ANTIBACTERIAL COMPOUNDS | SPOUT1, MRPL21, NRDC | GABRA1 3647/4885GABRB2 2626/4885MEN1 4365/4885 |
| US-20200255413-A1 | ANTIBACTERIAL COMPOUNDS | SPOUT1, MRPL21, NRDC | GABRA1 3647/4885GABRB2 2626/4885MEN1 4365/4885 |
| US-11021471-B2 | Antibacterial compounds | SPOUT1, MRPL21, NRDC | GABRA1 3647/4885GABRB2 2626/4885MEN1 4365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.