Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192 | 0.87 | ALDH1A1 (0.74) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11797328 | 0.84 | HPRT1 (0.54) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16670455 | 0.79 | HPRT1 (0.58) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22288225 | 0.79 | HPRT1 (0.58) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11826122 | 0.78 | TRPM4 (0.46) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1913996 | 0.77 | ALDH1A1 (0.46) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| Chrysene SCHEMBL384031 | 0.76 | HPRT1 (1.00) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| Chrysene SCHEMBL9786466 | 0.76 | HPRT1 (1.00) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25510 | 0.76 | HPRT1 (1.00) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| Chrysene SCHEMBL27115 | 0.76 | HPRT1 (1.00) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110215715-A1 | CHRYSENE COMPOUNDS FOR BLUE OR GREEN LUMINESCENT APPLICATIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| EP-2350230-A2 | CHRYSENE COMPOUNDS FOR BLUE OR GREEN LUMINESCENT APPLICATIONS | E. I. du Pont de Nemours and Company (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010059837-A2 | CHRYSENE COMPOUNDS FOR BLUE OR GREEN LUMINESCENT APPLICATIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110215715-A1 | CHRYSENE COMPOUNDS FOR BLUE OR GREEN LUMINESCENT APPLICATIONS | CRY2, CRY1, CYBA | HPRT1 929/4885ALDH1A1 2861/4885CYP1A2 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.