Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17358644 | 0.80 | GLA (0.33) | POLB | |
| SCHEMBL17358658 | 0.74 | POLB (0.31) | POLB | |
| SCHEMBL4439260 | 0.63 | PTPN1 (0.34) | — | |
| SCHEMBL6948155 | 0.57 | ACHE (0.32) | — | |
| SCHEMBL12844899 | 0.57 | ACHE (0.32) | — | |
| SCHEMBL8121841 | 0.55 | SORT1 (0.30) | — | |
| SCHEMBL5751012 | 0.54 | PTPN1 (0.33) | — | |
| SCHEMBL125436 | 0.54 | POLB (0.39) | POLB | |
| SCHEMBL4439425 | 0.54 | LMNA (0.31) | — | |
| SCHEMBL31290853 | 0.52 | POLB (0.49) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527573-B1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2020-08-12 | — | — | EP | disclosed |