Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 5/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22334811 | 0.91 | ALDH1A1 (0.42) | ALOX15MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL22334786 | 0.88 | ALDH1A1 (0.44) | ALOX15MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL4220388 | 0.86 | HDAC3 (0.49) | DGKAELANEPAMMEN1ALDH1A1 | |
| SCHEMBL4210162 | 0.86 | HDAC3 (0.49) | DGKAELANEPAMMEN1ALDH1A1 | |
| SCHEMBL4212739 | 0.86 | HDAC3 (0.49) | DGKAELANEPAMMEN1ALDH1A1 | |
| SCHEMBL4207148 | 0.86 | HDAC3 (0.49) | DGKAELANEPAMMEN1ALDH1A1 | |
| SCHEMBL4216103 | 0.86 | HDAC3 (0.49) | DGKAELANEPAMMEN1ALDH1A1 | |
| SCHEMBL4213343 | 0.86 | HDAC3 (0.49) | DGKAELANEPAMMEN1ALDH1A1 | |
| SCHEMBL22337056 | 0.84 | ALDH1A1 (0.43) | ALOX15MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL3814877 | 0.83 | DGKA (0.60) | DGKAP2RX7ELANEPAMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4039220-B1 | DENTAL MATERIALS ON THE BASIS OF POLYMERISABLE THIOUREA DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2022-12-28 | — | — | EP | disclosed |
| US-11357709-B2 | Dental materials based on redox systems with low-odour cumene hydroperoxide derivatives | IVOCLAR VIVADENT AG (LI) | 2022-06-14 | — | — | US | disclosed |
| EP-3692976-B1 | DENTAL MATERIALS BASED ON REDOX SYSTEMS WITH LOW ODOR CUMENE HYDROPEROXIDE DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2021-03-31 | — | — | EP | disclosed |
| US-20200253837-A1 | Dental Materials Based On Redox Systems With Low-Odour Cumene Hydroperoxide Derivatives | IVOCLAR VIVADENT AG (LI) | 2020-08-13 | — | — | US | disclosed |
| EP-3692976-A1 | DENTAL MATERIALS BASED ON REDOX SYSTEMS WITH LOW ODOR CUMOLHYDE-HYDROPEROXIDE DERIVATIVES | Ivoclar Vivadent AG (LI) | 2020-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11357709-B2 | Dental materials based on redox systems with low-odour cumene hydroperoxide derivatives | GPX4, GPX1, AOX1 | DGKA 2025/4885P2RX7 1742/4885ELANE 3222/4885 |
| US-20200253837-A1 | Dental Materials Based On Redox Systems With Low-Odour Cumene Hydroperoxide Derivatives | GPX4, GPX1, AOX1 | DGKA 2025/4885P2RX7 1742/4885ELANE 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.