Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 3/20 | 0.44 |
| ▸ | DHFR | P00374 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22334971 | 0.92 | RAB9A (0.62) | MAPTRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL22334924 | 0.79 | MAPT (0.57) | MAPTRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL18003335 | 0.79 | MAPT (0.54) | MAPTRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL22334847 | 0.76 | RAB9A (0.44) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL18674597 | 0.73 | RAB9A (0.84) | MAPTRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL3066594 | 0.73 | HSD17B10 (0.58) | MAPTRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL18003332 | 0.72 | MAPT (0.52) | MAPTRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL28699866 | 0.71 | DHFR (0.50) | MAPTRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL29671544 | 0.70 | DHFR (0.46) | MAPTRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL22334799 | 0.70 | NOTUM (0.48) | CYP2C19MEN1HPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3142638-B1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | OREAL (FR) | 2020-08-12 | — | — | EP | disclosed |